Development and Evaluation of a Lifestyle Intervention Among Participants of the French Colorectal Cancer Screening Program

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The investigators propose a randomized controlled trial to develop and evaluate the impact of promoting advice on diet and lifestyle recommendations for cancer prevention at colorectal cancer screening among individuals who may be at higher risk for colorectal cancer (CRC). The specific objectives of this study are to 1) develop a lifestyle intervention based on evidenced-based diet and lifestyle recommendations (i.e. those proposed by the World Cancer Research Fund (WCRF) and the French National Cancer Institute); 2) evaluate the effect of the intervention on the adherence to the target diet and lifestyle recommendations as well as other subjective health measures, including quality of life; 3) evaluate the effect of the intervention on biological pathways linked to colorectal cancer development including physical fitness, anthropometrics, biomarkers for nutrition, and metabolic health.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 65
Healthy Volunteers: t
View:

• At high risk for CRC but CRC negative (confirmed by colonoscopy)

• Able to provide informed consent

• Understanding and able to speak French

Locations
Other Locations
France
International Agency for Research on Cancer
RECRUITING
Lyon
Contact Information
Primary
Marc J Gunter, PhD
GunterM@iarc.fr
0033472738093
Backup
Inge Huybrechts, PhD
HuybrechtsI@iarc.fr
0033472738148
Time Frame
Start Date: 2022-03-23
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 500
Treatments
Active_comparator: Intervention
Colorectal cancer free participants receive evidence-based diet and lifestyle advice in addition to the 'usual care' following a positive FIT test and diagnostic colonoscopy
No_intervention: Control
Colorectal cancer free participants receive the 'usual care' following a positive FIT test and diagnostic colonoscopy
Related Therapeutic Areas
Sponsors
Collaborators: University of Bordeaux, Centre Leon Berard, Hôpital Edouard Herriot
Leads: International Agency for Research on Cancer

This content was sourced from clinicaltrials.gov